AstraZeneca’s Tozorakimab Clears Key COPD Trials, Bolstering $5 Billion Sales Ambitions

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‼️ 🇬🇧 AstraZeneca released full results from two successful late-stage trials of tozorakimab, an experimental therapy for chronic obstructive pulmonary disease (COPD), reinforcing expectations that it could become a breakthrough treatment and achieve peak annual sales exceeding $5 billion. The data showed the drug significantly reduced flare-ups across a broad range of patients, strengthening the case for its potential as a leading COPD therapy.

Singapore Backs SIA’s Global Push—Even Into Turbulent Skies

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‼️ ✈️ 🇸🇬 Singapore’s government supports Singapore Airlines’ overseas investments, including financial backing for loss-making Air India, as it seeks to build a stronger global presence. Transport Minister Jeffrey Siow said competing internationally requires entering difficult markets, challenging established players and staying committed through periods of turbulence.

OpenAI Anchors Firmus’ Malaysia AI Buildout, Lifting Contracted Capacity Above 900 MW

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‼️ 🧠 🇦🇺 Australia-based AI infrastructure firm Firmus Technologies has signed a multi-year deal to provide OpenAI with dedicated computing capacity from two Malaysian data centers, making the ChatGPT creator an anchor customer. The agreement pushes Nvidia-backed Firmus’ total contracted capacity above 900 MW, as it expands beyond its operating sites in Australia and Singapore with five additional Asia-Pacific facilities under development. Its investors include Nvidia, Jane Street, Blackstone funds, and Coatue Management

Canada Hits Back: 15–50% Retaliatory Tariffs Target U.S. Swing States to Force Trump Back to the Table

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‼️ 🇨🇦 On Tuesday, Canada imposed retaliatory tariffs of 15% to 50% on hundreds of U.S. products, a move Prime Minister Mark Carney is using to strengthen Ottawa’s negotiating position with Washington amid escalating trade tensions with President Donald Trump. The duties target U.S. exporters in politically sensitive swing states such as Michigan and Ohio ahead of November’s midterm elections, aiming to make the economic cost of the trade war tangible for American businesses and consumers and thereby pressure Washington to return to negotiations.

Foreign Investors Ditch Treasurys for Record U.S. Equity Bets

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‼️ Overseas investors are making a historic pivot from U.S. Treasurys to equities, as foreign ownership of government debt has fallen from more than 50% at its peak to about 30% today. By contrast, foreign holdings of U.S. stocks have reached record highs, with the country attracting a record $600 billion in net equity inflows in the year through March 2026.

China’s Trade Surge: Exports Accelerate to 25%, Surplus Balloons to $119B

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‼️ 🇨🇳 China’s exports grew 25% year-over-year in August, matching analysts’ forecasts and accelerating from July, while imports rose 28.2%, slightly below the 30% consensus but up from 27.5% the prior month; together, the stronger export momentum and resilient import demand pushed China’s trade surplus to $119.09 billion, widening from $112.5 billion in July.